Interleukin-1 and tumor necrosis factor- mediation of endotoxin action on growth hormone
نویسندگان
چکیده
J. A. Daniel, T. H. Elsasser, A. Martı́nez, B. Steele, B. K. Whitlock, and J. L. Sartin Animal and Range Sciences, South Dakota State University, Brookings, South Dakota; United States Department of Agriculture-Agricultural Research Service Growth Biology Laboratory, Beltsville; Cell and Cancer Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; and Department of Anatomy, Physiology, and Pharmacology, Auburn University, Auburn, Alabama
منابع مشابه
Inhibiting interleukin-1 and tumor necrosis factor-alpha does not reduce induction of plasminogen activator inhibitor type-1 by endotoxin in rats in vivo.
In experimental animals and humans, intravenous (i.v.) injection of endotoxin induces large increases in circulating plasminogen activator inhibitor type-1 (PAI-1), a major inhibitor of blood fibrinolysis. A similar increase is seen after the injection of interleukin-1 (IL-1) or of tumor necrosis factor-alpha (TNF-alpha), suggesting that these cytokines mediate the induction, by endotoxin, of P...
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تاریخ انتشار 2005